Frederick Wittke | Vaccines Clinical Development Team Lead Europe
Independent

Frederick joined MSD in November 2016 to build a European Vaccines Clinical Development Unit in Europe. His team now has four members. This team designs, sets-up, conducts, monitors, analyzes, closes out and publishes clinical trials and PDTs within a broader clinical trial teams for vaccine candidate programs within our company. As part of the Global Clinical Development Team his team provides unique European landscape and clinical development expertise to headquarters teams to inform upper management and PDTs supporting them in their decision-making process. His team contributes to filings, starting with Pediatric Investigational Plans and product candidate filings to EMA and other non-EU health authorities. His team also provides pipeline related information to local health authorities as well as to local conferences on candidate vaccine products, in collaboration with local Medical Affairs teams.   Frederick started his path in the Immunotherapy Unit in Oncology as Investigator for Oncology Clinical Trials and designed Dendritic Cell derived immunotherapy trials for Renal Cell Carcinoma and Metastasized Malignant Melanoma patients in Hannover, Germany. At INSERM he worked as Post Doc in Immune-genetics of autoimmune diseases at Hôpital Necker Paris. He later worked in Clinical Microbiology, researching glycolipids as targets for new M. tuberculosis vaccines (5th EU Framework), Joining Miltenyi Biotec GmbH leading Medical Affairs and Clinical Development Programs. Learning Clinical Development within Big Pharma (GSK, Novartis) conducting various clinical trials including a maternal immunization program. Leading an antimicrobial agent program at Debiopharm before joining MSD. Frederick successfully finalized AKAD Chemistry Studies by correspondence in 1990. He graduated from Medical School Hannover in Germany back in 1997. His thesis on Immune toxicology was prepared at Fraunhofer Institute for Toxicology and Aerosol Research and he successfully defended in 1997. Frederick has over 30 years of teaching experience in the medical and clinical development field. He collaborated with the University of Geneva where he contributes to the Biomedical Science curriculum and he is collaborating with the Tel Aviv University for a “Clinical Development and Regulatory Science”-curriculum, contributing with a condensed summer course on Vaccinology. Frederick has authored multiple publications in various fields including Oncology, Immunology, Vaccinology, Infectious Disease Development and recently Modelling.