Julien MUZARD | Field Application Technologist
Entegris
Julien's career has been devoted to the discovery & development of new technologies to help solve of the world's most complex design challenges, from the treatment of human diseases by creating new therapeutic libraries, to the manufacture of smart nano-electronics & 3D infrastructures. He designs programmable matter to build applications across all scales & domains. Julien’s pioneered work on combinatorial & structure-based design of recombinant antibodies & synthetic peptides has been used as framework to develop several therapeutic/theragnostic molecules used in clinical stage &/or commercially. He also made significant contribution to the manufacture of other genetically engineered structures, composite particles & hardware systems. Julien studied diagnostic microbiology, toxinology, molecular biology & immunotherapeutics, then obtained his PhD. After postdoctoral fellowships, Dr. Muzard continued his career abroad & then returned to Europe. Julien is now working on the field as a technologist within the global Application Team at Entegris Life Science.
Appearances:
Festival of Biologics Day 1 @ 16:10
Precision controlled biomanufacturing using off the shelf, ready-to-use components: from bench to clinic
Precision-controlled biomanufacturing, cell processing tools, and particle separation technologies are pivotal in the production of Advanced Therapy Medicinal Products (ATMPs), synthetically cultured biologics, and laboratory-grown food. As the demand for efficient, consistent, high-performance, and scalable manufacturing solutions intensifies, adaptable downstream cell processing platforms have become essential. Single-use systems offer a promising solution by providing operational simplification, reduced cross-contamination risks, flexibility, and minimal downtime. Nevertheless, the validation of these systems remains a critical concern, necessitating assurance of consistent performance, material compatibility, integrity, sterility, and regulatory compliance.
This session will present data from the development of a ready-to-use, sterile plug-and-play assembly designed to streamline critical processes such as cryo-preservation, cell banking, mammalian cell growth, separation, filling, and storage applications. We will also explore key validation considerations for single-use systems, highlighting the challenges and risks associated with transitioning from traditional aseptic technologies to innovative alternatives like the featured plug-and-play assembly.
Attendees will gain valuable insights into cutting-edge systems utilized across the life sciences and the meticulous steps required for their successful validation
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