Thomas Rose | Head of Expression Systems
ProBioGen AG

Festival of Biologics Day 1 @ 17:30

Directed Luck®: Transposase targeting and Transposon design push expression beyond limits

Transposases have eased cell line development. Taking this concept to a new level, we equipped our hyperactive transposase with epigenetic readers that targets highly active genomic sites in the host cell line and designed advanced transposons with optimized ITRs for most efficient and clean integration. DirectedLuck® delivers highly productive clones and bulk pools ready for manufacturing and is particularly suited for heterodimeric formats, polyclonal antibody cell lines and viral vector packaging cell lines.

Thomas Rose, Head of Expression Systems, ProBioGen AG

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Thomas Rose / Directed Luck®: Transposase targeting and Transposon design push expression beyond limits

Thomas Rose, Head of Expression Systems,
ProBioGen AG

Thomas Rose, PhD, is Head of Expression Systems at ProBioGen. He received his MSc in Biotechnology from the University of Applied Science in Berlin, his PhD in Biochemistry from the Free University of Berlin and joined ProBioGen in 2001. His work focuses on cell line development and expression...

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